TLDR: FoundersX Managing Partner Helen Liang, PhD, announced that the firm’s portfolio companies have collectively raised more than $120 million in Series A funding. This significant capital infusion is attributed to the transformative impact of generative AI (GenAI) across high-growth sectors including cybersecurity, fintech, and healthcare, underscoring FoundersX’s AI-first investment strategy.
FoundersX Ventures, a prominent AI-first venture capital firm established in 2016, has announced a major milestone: its portfolio companies have successfully secured over $120 million in Series A funding. This achievement was highlighted by Managing Partner Helen Liang, PhD, and reported by Business Insider on October 9, 2025. The substantial investment reflects a strong market confidence in companies leveraging generative AI (GenAI) to drive innovation and growth.
The funding rounds underscore the increasing influence of GenAI across critical industries. FoundersX’s investment strategy is deeply rooted in identifying and nurturing companies that are at the forefront of AI transformation and digital infrastructure development. The firm specializes in enterprise SaaS, Fintech, digital health, and life sciences, sectors where AI-driven solutions are creating unprecedented value.
FoundersX categorizes its investments into three key areas:
GenAI Infrastructure: This segment focuses on foundational compute infrastructure, including AI chips, quantum computing, and autonomous robotics. These technologies are crucial for reducing AI compute costs, enhancing efficiency, and overcoming scalability bottlenecks.
Deep Domains: This portfolio targets industries like fintech, healthcare, and enterprise solutions, where AI-driven intelligence and cross-modality data are unlocking new value. These companies are actively redefining traditional sectors with cutting-edge GenAI applications.
GenAI Agents: This area involves companies that bring AI into real-world applications, personalizing and enhancing experiences in healthcare, finance, entertainment, and commerce.
The firm’s success is attributed to its ‘Power Law’ strategy, which includes deep-dive research to gain intuitive insights, a contrarian approach to identify overlooked opportunities, and a high value-add model that provides portfolio companies with access to top talent, long-term capital partners, and a strategic enterprise network. FoundersX boasts a strong track record, with 120 founders, 30 companies valued over $100 million, 9 unicorns, and 10 acquired companies in its portfolio.
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Helen Liang, PhD, leads the firm as Managing Partner, alongside General Partners Leo Cui, PhD, and Sizi Chen. The firm recently expanded its presence by opening an NYC office on October 17, 2025, further solidifying its position at the epicenter of innovation.
