TLDR: The research paper “In Reverie Together: Ten Years of Mathematical Discovery with a Machine Collaborator” details the journey of TxGraffiti, an AI system that generates mathematical conjectures in graph theory. It highlights the system’s collaborative development with human mathematicians and presents four significant open conjectures that remain unsolved. The paper also discusses a future vision for fully automated mathematical discovery involving interacting AI agents for conjecturing, proving, and refuting.
For a decade, the automated conjecturing system TxGraffiti has been a silent partner in mathematical discovery, particularly in graph theory. This system, a brainchild of researchers including Randy Davila, Boris Brimkov, and Ryan Pepper, has not only generated hundreds of mathematical conjectures but has also fostered a unique collaboration between humans and machines in the pursuit of new mathematical truths. The paper, titled “In Reverie Together: Ten Years of Mathematical Discovery with a Machine Collaborator”, delves into this journey, highlighting four significant open conjectures that continue to challenge mathematicians worldwide. You can read the full paper here.
The Genesis of TxGraffiti
TxGraffiti is an automated framework designed to propose mathematical conjectures, primarily in graph theory, in the form of inequalities and equalities. Inspired by earlier systems like Graffiti, it operates by analyzing precomputed data of graph invariants and employing optimization routines and heuristic filters to identify novel and empirically valid statements. Since its inception, TxGraffiti has contributed to numerous mathematical publications, demonstrating its capability to generate ideas that lead to verifiable advances in mathematics.
Human-Machine Collaboration: A Driving Force
A crucial aspect of TxGraffiti’s success lies in its continuous collaboration with human mathematicians. These experts act as guides in the system’s design and critical evaluators of its output. They test conjectures, offer counterexamples, and provide feedback that refines the system’s ability to identify mathematically relevant statements. This iterative process, where human insight drives the refinement of machine-generated ideas, has been fundamental to the project’s progress. The conjectures often point to genuinely unexplored territory, requiring new structural insights for their proofs.
Four Enduring Challenges
The paper presents four open conjectures generated by TxGraffiti, each chosen for its structural appeal, empirical sharpness, and resistance to proof or disproof. These are not just technical problems but creative expressions born from symbolic pattern recognition and refined through years of human dialogue.
The first, Conjecture 1 (Open Since 2016), proposes a surprising lower bound on the independence number of a graph, linking it to the annihilation number, residue, and maximum vertex degree. It combines fundamentally disparate bounds to produce a new one.
Next is the (α, Z)-conjecture (Open Since 2017), which relates the zero forcing number and the independence number in connected graphs with a maximum degree of three (excluding K4). This conjecture has garnered considerable attention and has been proven or strengthened under specific structural assumptions.
The third, Conjecture 3 (Open Since 2020), is a “mirror conjecture” on independent domination and maximal matchings. It suggests a simple inequality between the independent domination number and the minimum cardinality of a maximal matching in r-regular graphs. This parallels earlier findings about independence and matching numbers, highlighting a symmetry between vertex- and edge-based packing parameters.
Finally, Conjecture 4 (Open Since 2023), links the continuous harmonic index of a graph to the discrete size of a smallest maximal matching. This is conceptually surprising, as few known results connect the harmonic index to saturation-based or combinatorial matching parameters. Empirical validation shows that the size of a smallest maximal matching is bounded above by the graph’s harmonic index.
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Towards Fully Automated Discovery
Looking ahead, the authors envision a future where the entire cycle of conjecture, evaluation, proof, and refutation can be fully automated. This involves a “constellation of interacting AI agents,” including a conjecturer (like TxGraffiti, or its evolving form, the Optimist), a prover, and a counterexampler (the Pessimist). This architecture mirrors the collaborative human process but aims to complete the cycle without human intervention, opening the door to a new kind of mathematics that is recursive, collaborative, and unconstrained by human limitations.
These conjectures are more than just mathematical problems; they are artifacts of a shared creative process between humans and machines, pointing toward a future where artificial agents participate meaningfully in the pursuit of mathematical knowledge.


